Stereology Blog

Reliable stereology information is critical for publications and research proposals. Reviewers understand that unbiased (design-based) stereology is now considered best practices for quantitative analysis of biological tissue.

Our mission at SRC Biosciences is to equip biomedical scientists with the computerized technology, contract services and training to apply these powerful methods.

The Stereology Blog allows us to share new and relevant information to the stereology practitioners around the world.

SRC Biosciences

A new stereology time-course study by Pfizer Inc. in collaboration with SRC Biosciences finds no neuroregeneration in the rat superior cervical ganglion (SCG) after neuron death. This study addresses the critical issue of neuroregeneration in the ganglia of the sympathetic division of the autonomic nervous system. new stereology time-course study TH-stained sections of rat SCGDespite evaluating neuron numbers in the rat SCG at 1, 3, and 6 months after nerve death, postganglionic neurons were not restored.  This work has important implications for recovery of the “flight or flight” response after surgery or traumatic brain injury. The SCG provides sympathetic innervation to many structures in the head, including the blood vessels in the cranial muscles and the brain, the choroid plexus, the eyes, the lacrimal glands, salivary glands and the thyroid gland.

Citation: Walters, K. M., Boucher, M., Boucher, G. G., Opsahl, A. C., Mouton, P. R., Liu, C.-N., … Somps, C. J. (2019). No Evidence of Neurogenesis in Adult Rat Sympathetic Ganglia Following Guanethidine-Induced Neuronal LossToxicologic Pathology.

April “Free For All” Stereology Webinar

Dr. Peter R. Mouton, Professor of Stereology (University of So. Fla, Tampa) and Director & Chief Scientific Officer at SRC Biosciences, will host the SRC’s April “Free For All” Stereology Webinar.

The date and time will be Wednesday, April 17, 2019, from 12:00 noon to 2:00 pm.Stereological Bias

Agenda
  • 12-12:50 pm: Overview of practical methods for avoiding methodological bias in stereology studies.
  • 1-1:50 pm Update on NSF-funded project to automate the stereology data collection(currently in beta testing).
  • After each presentation, there will be a 10-min Q&A session/break.
If you have any specific stereology questions, please submit them to src@disector.com prior to the stereology webinar.
The stereology webinar is free but you must register at https://www.stereologyresourcecenter.com/contact-us/. We will send out the GoToMeeting login invitation prior to the April webinar date.