Stereology Contract Research Organization
SRC Biosciences (Stereology Resource Center, Inc.) is the longest-running stereology contract research-organization in existence (1995-present).
Our stereology contract research organization has completed hundreds of outsourcing projects for academic institutions, government agencies and private pharmaceutical companies worldwide.
We are the only stereology contract research organization with professional consulting, tissue processing and expert data collection available to all our clients.
Our Services. Our Stereology CRO provides:
- Accurate stereology analysis of your stained sections
- State-of-the-art tissue processing for stereology analysis
- No-cost Professional stereology consultation
- Rapid turn-a-round
- Compliant with requirements for peer review journals, grant proposals, and regulatory agencies
Stereology Contract Research
Our Stereology CRO services continue to meet demand for stereology data for research projects in academia, government agencies and the pharmaceutical industry. A few examples from hundreds of peer-reviewed studies:
Marcek, J., et al., Anti-NGF Monoclonal Antibody mu Mab 911 Does Not Deplete Neurons In The Superior Cervical Ganglia Of Young Or Old Adult Rats. J Chem Neuroanat. 76: 133 2016.
Stoner, R., et al., Discrete Patches of Laminar Disorganization in Young Autistic Neocortex, New England Journal of Medicine, March 17, 2014.
Courchesne, E., Mouton, P.R., et al., Neuron Number And Size In Prefrontal Cortex Of Children With Autism. Journal Of The American Medical Association (JAMA), 306 (18):2001-10, November 9, 2011.
Weise, C. M., et al. A Post-Mortem Stereological Study Of Striatal Cell Number In Human Obesity. Obesity, 23(1):100-4, 2015.
Harry, G.J., et al., Neurodevelopmental Effects Of Gestational And Perinatal Thyroid Disruption In Rats. Toxics, 2, 496-532, 2014.
Computerized Stereology Systems. In the mid 1990s the SRC was one of the first companies to reduce unbiased stereology to a computerized platform. Since then, the Stereologer system has completed over four thousand stereology projects for the global bioscience community.
Stereology Innovations. With extensive support from federal and private grants for new innovations, SRC Biosciences has transformed the Stereologer into the most user-friendly, comprehensive system for automated stereology. Among the innovations first introduced in the Stereologer software include:
Automated counts of total number of immunostained neurons (Mouton, P.R., et al., J Chem Neuroanat, 2017).
Automatic section thickness determination for stereology (Elozory, D., et al., Journal of Microscopy, 2012).
The Rare Event Protocol (Mouton, P.R. Unbiased Stereology: A Concise Guide. The Johns Hopkins University Press, Baltimore, August, 2011.
Surface area and surface density using unbiased virtual cycloids (Gokhale, A.M., et al., Journal of Microscopy, 2004).
Unbiased estimation of length and length density on sections cut at any orientation (Mouton, P.R., et al., Journal of Miccroscopy, 2002).
Stereology Workshops and Webinars. From 1995 to the present, Dr. Peter R. Mouton and SRC-sponsored 2 to 5 day workshops and free monthly webinars have trained 4000+ scientists (and counting!).
Stereology Expertise. The expertise behind SRC Biosciences continues to inform and educate through peer-reviewed books, book chapters and review articles:
Mouton, P.R. Neurostereology, Wiley-Blackwell Press, Boston, 280 pages, November 2013.Mouton, P.R. Quantitative Anatomy Using Unbiased Stereology, in CRC Handbook of Imaging in Biological Mechanics (Corey P. Neu and Guy M. Genin, eds), CRC Press, London, October 23, 2014.
Mouton, P.R. Applications Of Unbiased Stereology To Neurodevelopmental Toxicology, In Developmental Neurotoxicology Research: Principles, Models, Techniques, Strategies And Mechanisms (C. Wang And W. Slikke, Eds), John Wiley & Sons, Hoboken, pg. 53-77, 2011.
Mouton, P.R. Unbiased Stereology: A Concise Guide. The Johns Hopkins University Press, Baltimore, August, 2011.
Mouton PR. Principles And Practices Of Unbiased Stereology: An Introduction For Bioscientists. The Johns Hopkins University Press, Baltimore, Maryland, May 2002.
Confidentiality. All Stereology Contract Research Organization work is carried out under strict confidentiality and blind to treatment.
Good Laboratory Practices (GLP). Compliance with GLP is available for products regulated by the Food and Drug Administration, including food and color additives, animal food additives, human and animal drugs, medical devices for human use, biological products, and electronic products. This compliance is intended to assure the quality and integrity of the safety data filed pursuant to regulatory sections of the Code of Federal Regulations (Title 21, parts 11 and 58) and sections 406, 408, 409, 502, 503, 505, 506, 510, 512-516, 518-520, 721, and 801 of the Federal Food, Drug, and Cosmetic Act and sections 351 and 354-360F of the Public Health Service Act.