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Live remote support available or for help with a current project, call 410-739-1667 or click here.
To speak with one of our stereology experts, call 410-739-1667 or click here.
A sample of Frequently Asked Questions
A more or less clustered distribution does not affect accuracy but does require adjusting your sampling strategy to achieve maximal efficiency.
The Stereologer identifies the major sources of variability in your data and adjusts your sampling parameters accordingly. In this way the system automatically optimizes your sampling effort for maximum efficiency, which in turn increases your throughput, i.e., work completed per unit time.
The Corpuscle Problem refers to bias due to object size, shape, and orientation. All of these factors can introduce systematic error (bias) when attempting to count cells on stained tissue sections. The optical director first proposed by Gundersen (1986) uses the disector principle (Sterio, 1984) to avoid this bias by counting 3-D object during thin focal plane optical sectioning.
Our merit-based Stereology Fellowship Program offers full waiver of registration fees. Also, early registration allows students to take advantage of reduced registration fees and discounted rates on hotel rooms.
The Space Balls approach by Mouton et al. (2002) uses a sphere probe to quantify length of fibers, capillaries, etc. Because a sphere contains all integral angles, tissue sections can be cut at any convenient direction, e.g., coronal, horizontal. Prior to the Space Balls method, rotating tissue prior to sectioning caused serious problems with locating tissue landmarks. Also, tissue sections not previously rotated from older (archival) studies can now be analyzed without bias using the Space Balls method.
Recent publications from the SRC’s research program
