Dear Dr. Mouton, I have a stereology question. I’m comparing counts of TH immunostained (TH+) neurons in non-human primates (monkey) and mice. How do I account for variation in sampling area? For instance, there are obvious differences between mice and monkeys for the reference volume (substantia nigra, pars compacta, SNpc). Unless I control for these […]
Author Archive for: Peter
This author has yet to write their bio.Meanwhile lets just say that we are proud Peter contributed a whooping 2 entries.
Entries by Peter
During the past decade unbiased stereology approaches have become far more prevalent in the biosciences. Still, bioscientists often approach me and other stereologists with publications using biased stereology (assumption- and model-based methods) to quantify morphological endpoints. The questioner typically has a statement and/or question such as, “I want to quantify the same endpoint, e.g., total cell number. If […]