Special Issue on Automatic Stereology and Image Analysis

Drs. Peter R. Mouton and Hady Ahmady Phoulady have been selected to serve as Co-Editors for a Special Issue of the Journal of Chemical Neuroanatomy titled, “Automatic Stereology and Image Analysis: Novel Segmentation and Machine Learning Approaches.”

See Open Call for papers: https://www.journals.elsevier.com/journal-of-chemical-neuroanatomy/call-for-papers/special-issue-automatic-stereology-and-image-analysis

SRC awarded trademarks for stereology innovations. The United States Patent and Trademark Office recently awarded trademarks to the SRC for two innovative stereology approaches, “Rare EventMouton,Peter BRD_cover_2014 copy Protocol” (Mouton, 2011) and “Space Balls” (Mouton et al., 2002).

Pushing the Boundaries of Neuroscience. The Fall 2014 issue of Brain Research Discoveries features Peter R. Mouton, Ph.D., Chief Scientific Officer of the Stereology Resource Center (SRC).

“Dr. Mouton is the new breed of scientist/entrepreneur,” according to Dr. Marsha Gordon, Professor of Molecular Pharmacology & Physiology at the University of South Florida School of Medicine in Tampa, Florida.

“He runs his own company and knows how to talk to the business community, as well as do scientific research,” says Dr. Gordon. “That’s a new model institutions are interested in having on their faculty.”

Click here to read the complete interview with Dr. Mouton.

Stereology Innovation. A paper on automatic stereology for staging cervical cancer by Dr. Mouton and colleagues has been accepted for publication in the IEEE computer science journal, “Systems, Man, and Cybernetics.” The title of the work is Experiments in Large  Ensemble for Segmentation and Classification of Cervical Caner Biopsy Images. Click here for the abstract of this work.
UnbiasedBest selling stereology book. Online booksellers rank Unbiased Stereology: A Concise Guide from The John Hopkins University Press (Baltimore, MD) as the most popular stereology book on Amazon.com and BarnesandNoble.com. Rankings based on sales of hardcopy and e-booka offered by online booksellers.

 





logosTop Technology Innovator. Florida High Tech Magazine selected Peter R. Mouton, Ph.D., CEO of the SRC, as one of the twelve top technology entrepreneurs in the state of Florida for 2014.  Click here to see the online interview with Dr. Mouton.

 

Stereology News from the SRCHigh Impact Stereologer study. The SRC’s Stereologer system was used by researchers at the University of California at San Diego (UCSD, La Jolla, CA) and the University of South Florida School of Medicine (Tampa, FL)  to reveal the brain pathology underlying autism occurs prior to birth. This study published in the New England Journal of Medicine showed disorganized pattens of neurons in cortical brain regions associated with impaired social behavior in autistic children. Because patterns of neuron organization are established by the time of birth, these findings effectively rule out post-natal effects, e.g., vaccines, child rearing, as likely contributors to autism. The study points directly to mutations in genes controlling the patterning of neurons as the likely cause of autism.

  • March 2014. The SRC’s Stereology Core Facility receives a multi-year contract from the pharmaceutical industry to carry out drug safety studies in tissues from rats and non-human primates.
  • UAB LogoSpring Stereology Workshop at the University of Alabama, Birmingham (UAB). The SRC organized this comprehensive workshop held at UAB on March 6-7, 2014. Under the direction of Dr. Peter R. Mouton, this 2-day stereology short course taught by was well attended by UAB faculty, medical, graduate, and postdoctoral students.

More Stereology News From the SRC

  • NeurostereologyPurple1Neurostereology: Unbiased Stereology of Neural Systems (P.R. Mouton, Wiley-Blackwell Press, Boston, MA; published January 18, 2014). Hardback copies and digital e-versions from Amazon.com, BarnesandNobel.com, Apple iTunes, and other online booksellers.





  • Venue Selected for 20th Annual Fall Neurostereology Workshop. The Hilton Garden Inn has been selected for the Fall Neurostereology Workshop, “Applications of Unbiased Stereology To Neuronal Systems” to be held November 12-14, 2014 on the Chesapeake Bay (Kent Island, MD). To maintain an optimal instructor: participant ratio, seats for this popular workshop will be limited. Early registration is highly encouraged.
  • Fall Neurostereology Course.  The 19th consecutive Neurostereology Workshop, “Applications of Unbiased Stereology To Neuronal Systems,” was organized and taught by Professors Peter R. Mouton and Arun M. Gokhale on November 2013 in San Diego, CA, in conjunction with the Annual Meeting of the Society For Neurosciences.
  • SRC Stereology Fellowship Award. In November 2013 Ishrat Ahmed, an MD/Ph.D. student in the Department of Neuroscience at the Johns Hopkins University School of Medicine (Dr. Solomon Snyder, advisor), was awarded the 2013 Stereology Fellowship Award to the 19th Annual Fall Neurostereology Workshop in San Diego, CA. We would like to congratulate Ms. Ahmed for this important achievement and wish her best wishes in her future career.
  • Automatic Stereology Presentation. In September 2013 a paper co-authored by Dr. Mouton and collaborators was presented by SRC collaborator Dr. Dmitry Goldgof at the International Conference on Image Analysis and Processing (ICIAP) in Naples, Italy. The paper entitled, “An Ensemble Algorithm Framework For Automated Stereology Of Cervical Cancer,” appears in the peer-reviewed ICIAP Proceedings (Springer, Berlin, Vol 1:823-832, 2013). Funding for this work was provided by an SBIR grant (NIH) to the SRC.
  • Stereology Chapter in CRC Handbook. In July 2013, Dr. Mouton contributed a chapter, Quantitative Anatomy With Design-based Stereology, to the new edition of the CRC Handbook of Imaging in Biological Mechanics (C. Geu and G. Genin, eds), Taylor & Francis Press, New Yrok, in press.
  • American Association of Neuropathologists. Dr. Mouton delivered the Presidential Symposium. His talk entitled, “Applications of Unbiased Stereology To The Study Of Brain Disease,” was made at the Annual Meeting of American Association of Neuropathologists held at the Charleston Place Hotel, Charleston, SC on June 23, 2013.
  • Dr. Gokhale wins 2013 Sorby Award. Professor Arun M. Gokhale, co-founder with Dr. Peter Mouton of the Stereology workshop, “Applications of Unbiased Stereology To Neural Systems,” was awarded the prestigious Henry C. Sorby Award in May 2013 for his lifetime contributions to teaching, research and service.
  • 2013 Spring Neurostereology Workshop. The 2013 Spring Stereology Workshop was held on sunny Sanibel Island, Florida in April 2013.
  • HandBook Cover 250The Stereologer Handbook. Publication of the 5th edition of The Stereologer Handbook (Copyright SRC 2012). The Stereologer Handbook provides step-by-step instruction, high-resolution images, and up-to-date information on estimation of first- and second-order parameters using computerized stereology.

 

  • Two patent applications were filed by the SRC and the University of South Florida in support of an integrated hardware-software system for automatic collection of stereology data using Verified Computerized Stereoanalysis (VCS; Mouton et al., 2005; Chaudhury et al., 2013).
  • Trademark “Stereologer” awarded to the SRC by the U.S. Patent And Trademark Office on March 5, 2012 and published in the Trademark Official Gazette on May 8, 2012.
  • Unbiased Stereology: A Concise Guide. The Johns Hopkins University Press published “Unbiased Stereology: A Concise Guide” (August 2011). This well-written and well-illustrated text by Peter R. Mouton reviews the important theoretical and practical aspects of stereology as applied to biological tissue.  Available in paperback, hardback, and e-reader editions. Click here for information about ordering paperback, hardback, and e-editions.
  • Stereology News from the SRC JAMA.Pic.NewsHigh Impact Stereologer study [Neuron Number and Size in Prefrontal Cortex of Children With Autism, Journal of the American Medical Association (JAMA) 306(18):2001-2010, 2011]. This study lead by Dr. Eric Courchesne of the University of California (San Diego, CA) and Dr. Peter R. Mouton of the University of South Florida (Tampa, FL) used the Stereologer system to confirm an excess of neurons in the prefrontal cortex of autistic children aged 2 to 16 years. The authors acknowledge the generous support from the NIH and other funding sources, tissue collected by Autism Speaks, and the families of children with autism who donated tissue for this study.